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http://hdl.handle.net/2108/892
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| DC Field | Value | Language |
| contributor.advisor | Bardati, Fernando | - |
| contributor.author | Iudicello, Santina | - |
| date.accessioned | 2009-05-04T15:06:15Z | - |
| date.available | 2009-05-04T15:06:15Z | - |
| date.issued | 2009-05-04T15:06:15Z | - |
| identifier.uri | http://hdl.handle.net/2108/892 | - |
| description | 21. ciclo | en |
| description.abstract | Interest in breast imaging with electromagnetic fields in the
microwave band has been mainly motivated by certain deficiencies
in current screening and diagnostic practices based on X-ray
mammography.
In this thesis the feasibility of microwave radiometry as a
modality for early-stage breast cancer detection has been
investigated based on the tumor over-temperature rationale.
The goal of this work is to establish the rationale for the
application of microwave radiometry for breast cancer detection
and to provide the basis for setting-up measurements on patients.
Basing on electrical and thermal properties of breast tissue
available in the literature I developed a numerical model to
predict the radiometric output when a contacting antenna is
scanned on the breast surface. For this reason, a full 3D model
that relates radiometric data to the temperature difference
between normal and malignant breast has been developed in order to
predict the radiometric visibility of tumors.
Then, I found that the deformation by a cooled antenna pressed
against the breast lowers the distance of a subsurface tumor from
the contacted surface thus improving the tumor radiometric
visibility. I showed this result modeling breast deformation,
temperature distribution and corresponding radiometer output both
in the presence of a tumor and in its absence.
Two patch antennas have been designed to be matched to a
multilayer model of the breast. The antennas have been measured
on volunteers in a preliminary small-scale experimental study. By
estimating the antenna reflectivity I derived a requirement on
the residual temperature when non-ideal radiation balance
radiometer and antenna are considered.
Some measurements with the "Tor Vergata" radiometer are presented.
The radiometric resolution has been characterized when
a matched load immersed in a water bath is connected to the input of the radiometer. A breast phantom and a thermal anomaly
imitator for the mammary gland have been developed.
The results of phantom measurements give positive indication on
the feasibility of thermal spot detection by our radiometer. | en |
| description.tableofcontents | 1.An overview of the Breast Cancer Screening and Diagnostic Technologies - 2. Microwave Radiometry: Basic Principle - 3. Detectability of Tumor by a Radiometric System - 4. Breast Tissue Compression to Improve Radiometric Visibility - 5. Theorical and Experimental Characterization of the Radiometric Antenna - 6. Microwave radiation balance radiometer characterization | en |
| format.extent | 3869184 bytes | - |
| format.mimetype | application/pdf | - |
| language.iso | en | en |
| subject | microwave radiometry | en |
| subject | breast cancer detection | en |
| subject.classification | ING-INF/02 Campi elettromagnetici | en |
| title | La Radiometria a microonde per la diagnosi del tumore al seno | en |
| type | Doctoral thesis | en |
| degree.name | Dottorato in geoinformazione | en |
| degree.level | Dottorato | en |
| degree.discipline | Facoltà di ingegneria | en |
| degree.grantor | Università degli studi di Roma Tor Vergata | en |
| date.dateofdefense | A.A. 2008/2009 | en |
| Appears in Collections: | Tesi di dottorato in ingegneria
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Files in This Item:
| File |
Description |
Size | Format |
| PhD_thesis.pdf | | 3778Kb | Adobe PDF | View/Open |
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