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Please use this identifier to cite or link to this item: http://hdl.handle.net/2108/865

Title: Uso della cistatina C nella diagnosi di insufficienza renale acuta in terapia intensiva
Other Titles: Cystatin C as marker of acute renal injury in intensive care unit
Authors: De Lorenzo, Antonino
Di Daniele, Nicola
Ferrannini, Michele
Keywords: cistatina C
insufficiena renale acuta
Issue Date: 21-Apr-2009
Abstract: Timing to detect early stage of renal impairment is extremely important especially in the therapeutic management of complex illness. In acute condition, the absence of a reliable biomarker and the reliance on serum Cr (sCr) makes the diagnosis and consequently the institution of therapy markedly delayed. Recently, the research interest on serum CysC role in ICU-population has been stopped after the presumed association of CysC with inflammatory biomarkers in non-critical-ill patients. We retrospectively reviewed all laboratoristical data referral to 1000 patients (611 male, mean age 64,3) admitted in ICU or Post-Cardiac-Surgery-Intensive-Care-Unit (PCSICU). PCSICU population was submitted to extracorporeal circulation during cardiac surgical intervention. 3993 samples tested contemporaneously for sCr, CysC and C-Reactive-Protein (CRP) were selected. Renal replacement therapy and known thyreopathy were exclusion criteria. No correlation between CysC ...
Description: 21. ciclo
URI: http://hdl.handle.net/2108/865
Appears in Collections:Tesi di dottorato in medicina

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