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|Title: ||Ipotiroidismo subclinico materno come fattore di rischio per i difetti congeniti settali|
|Other Titles: ||Maternal subclinical hypothyroidism is a risk factor for fetal cardiac septal anomalies|
|Authors: ||Valensise, Herbert|
|Keywords: ||maternal hypothyroidism|
congenital cardiac anomalies
|Issue Date: ||16-Feb-2009 |
|Abstract: ||Background: Maternal clinical and subclinical hypothyroidism is linked with an increased risk of fetal cardiac structural anomalies. The report of the National Registry of Neonatal hypothyroidism support this finding allowing evidence of an increased incidence of these anomalies in neonates with congenital hypothyroidism.
Objective of the study : The identification of a correlation between congenital cardiac anomalies and maternal clinical and subclinical hypothyroidism.
Methods: A) With a retrospective study on the National Registry of Congenital hypothyroidism the incidence of congenital heart defects has been evaluated. Furthermore the risk of specific cardiac septal defects was calculated when maternal thyroid function was reduced or a goiter present. B) The evaluation of the risk for cardiac septal defects was then evaluated with a retrospective study identifying in patients with hypothyroidism in treatment before and during pregnancy. C) With a case control study maternal th...|
|Description: ||19. ciclo|
|Appears in Collections:||Tesi di dottorato in medicina|
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