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Please use this identifier to cite or link to this item: http://hdl.handle.net/2108/577

Title: Metodi di analisi basati sull’inibizione delle colinestrerasi per applicazioni nel campo ambientale e alimentare
Authors: Palleschi, Giuseppe
Arduini, Fabiana
Keywords: cholinesterase inhibition
nerve agents
Issue Date: 26-Aug-2008
Abstract: The increasing interest in analytical systems based on enzyme inhibition, as demonstrated by several recent reviews, shows the importance of this type of biosensings and biosensors in the field of environmental and food analysis. The advantages associated with these sensing devices, particularly the easiness in using them, combined with the low costs, make these biosensors suitable for "in situ" monitoring also by non skilled personnel. During the three years of my PhD thesis, a complete study of ChEs based biosensors for pesticides, nerve agents and aflatoxin B detection has been carried out. The interference of heavy metals occurring in the detection of pesticides based on free Acetylcholinesterase (AChE) inhibition, has been investigated. The study proposed a new approach to overcome the interferences by the interaction between thiocholine and heavy metals using two different phases with a good sensitivity (an inhibition of 50% has been observed with 9⋅10-7 M of paraoxon). An al...
Description: 19. ciclo
URI: http://hdl.handle.net/2108/577
Appears in Collections:Tesi di dottorato in scienze matematiche e fisiche

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titolo.pdfFrontpage15KbAdobe PDFView/Open
Indice.pdfTable of contents32KbAdobe PDFView/Open
conclusioni.pdfConclusions58KbAdobe PDFView/Open
cap V.pdfChapter 5136KbAdobe PDFView/Open
cap IV.pdfChapter 4237KbAdobe PDFView/Open
cap III.pdfChapter 3174KbAdobe PDFView/Open
cap II.pdfChapter 2235KbAdobe PDFView/Open
cap I.pdfChapter 1627KbAdobe PDFView/Open

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