DSpace - Tor Vergata >
Facoltà di Scienze Matematiche Fisiche e Naturali >
Tesi di dottorato in scienze matematiche e fisiche >
Please use this identifier to cite or link to this item:
|Title: ||Metodi di analisi basati sull’inibizione delle colinestrerasi per applicazioni nel campo ambientale e alimentare|
|Authors: ||Palleschi, Giuseppe|
|Keywords: ||cholinesterase inhibition|
|Issue Date: ||26-Aug-2008 |
|Abstract: ||The increasing interest in analytical systems based on enzyme inhibition, as demonstrated by several recent reviews, shows the importance of this type of biosensings and biosensors in the field of environmental and food analysis.
The advantages associated with these sensing devices, particularly the easiness in using them, combined with the low costs, make these biosensors suitable for "in situ" monitoring also by non skilled personnel.
During the three years of my PhD thesis, a complete study of ChEs based biosensors for pesticides, nerve agents and aflatoxin B detection has been carried out.
The interference of heavy metals occurring in the detection of pesticides based on free Acetylcholinesterase (AChE) inhibition, has been investigated. The study proposed a new approach to overcome the interferences by the interaction between thiocholine and heavy metals using two different phases with a good sensitivity (an inhibition of 50% has been observed with 9⋅10-7 M of paraoxon).
|Description: ||19. ciclo|
|Appears in Collections:||Tesi di dottorato in scienze matematiche e fisiche|
Files in This Item:
|Indice.pdf||Table of contents||32Kb||Adobe PDF||View/Open|
|cap V.pdf||Chapter 5||136Kb||Adobe PDF||View/Open|
|cap IV.pdf||Chapter 4||237Kb||Adobe PDF||View/Open|
|cap III.pdf||Chapter 3||174Kb||Adobe PDF||View/Open|
|cap II.pdf||Chapter 2||235Kb||Adobe PDF||View/Open|
|cap I.pdf||Chapter 1||627Kb||Adobe PDF||View/Open|
Show full item record
All items in DSpace are protected by copyright, with all rights reserved.