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Please use this identifier to cite or link to this item: http://hdl.handle.net/2108/493

Title: Community acquired methicillin-resistant staphylococcus aureus: is an Italian emergence?
Authors: Pantosti, Annalisa
Monaco, Monica
Keywords: staphylococcus aureus
necrotising pneumonia
Panton-Valentine leukocidin
Issue Date: 14-May-2008
Abstract: Introduction Methicillin-resistant Staphylococcus aureus (MRSA) emerged as a cause of hospital infection in 1961, only two years after the introduction of methicillin. In Italy the rate of MRSA in hospital is very high (39-41%) and it is stable since many years. In the last years, there have been several reports of community-acquired MRSA (CA-MRSA) which differ from hospital-acquired MRSA strains (HA-MRSA) for a susceptibility profile with resistance to fewer classes of antibiotics and for the presence of specific virulence factors such as the Panton-Valentine Leukocidin toxin. Moreover CA-MRSA were found to contain SCCmec type IV or V. Objectives The aim of this study was to investigate if CAMRSA strains were present in Italy since they have been detected not only in North America, but also in Europe; second, to examine these strains both epidemiologically and microbiologically; third, to establish any clonal relatedness in order to compare CA-MRSA clones circulating in It...
Description: 19. ciclo
URI: http://hdl.handle.net/2108/493
Appears in Collections:Tesi di dottorato in medicina

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