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Tesi di dottorato in medicina >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/2108/493
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| Title: | Community acquired methicillin-resistant staphylococcus aureus: is an Italian emergence? |
| Authors: | Pantosti, Annalisa Monaco, Monica |
| Keywords: | staphylococcus aureus CA-MRSA infections necrotising pneumonia Panton-Valentine leukocidin |
| Issue Date: | 14-May-2008 |
| Abstract: | Introduction Methicillin-resistant Staphylococcus aureus (MRSA) emerged as a
cause of hospital infection in 1961, only two years after the introduction of
methicillin. In Italy the rate of MRSA in hospital is very high (39-41%) and it is
stable since many years. In the last years, there have been several reports of
community-acquired MRSA (CA-MRSA) which differ from hospital-acquired
MRSA strains (HA-MRSA) for a susceptibility profile with resistance to fewer
classes of antibiotics and for the presence of specific virulence factors such as the
Panton-Valentine Leukocidin toxin. Moreover CA-MRSA were found to contain
SCCmec type IV or V. Objectives The aim of this study was to investigate if CAMRSA
strains were present in Italy since they have been detected not only in
North America, but also in Europe; second, to examine these strains both
epidemiologically and microbiologically; third, to establish any clonal relatedness
in order to compare CA-MRSA clones circulating in It... |
| Description: | 19. ciclo |
| URI: | http://hdl.handle.net/2108/493 |
| Appears in Collections: | Tesi di dottorato in medicina
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| Monaco tesi dottorato.pdf | | 18491Kb | Adobe PDF | View/Open |
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